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MM927 [CAS 3065567-21-4]

MM927 [CAS 3065567-21-4]

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SKU:QM-0013418-01

£1,255.28 GBP
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  • Description

    MM927 is a potent NVL inhibitor, with an IC50 of 0.053 μM. MM927 blocks 60S ribosomal subunit biogenesis in the nucleolus. MM927 induces half-mer polysomes, cell cycle arrest at G1/S and G2/M and apoptosis in cells. MM927 demonstrates antitumor efficacy in MOLM-13 AML and HCT116 CRC xenograft models. MM927 can be used for the study of cancers such as acute myeloid leukemia (AML) and colorectal cancer (CRC) [1].

  • CAS Number

    [3065567-21-4]

  • Molecular Formula

    C26H18FN3O4S

  • Molecular Weight

    487.5

  • Smiles

    O=C1OC2=CC=C(C(NC3=CC=C4C(SC5=CC(F)=CC=C5C(N4CC#CC)=O)=C3)=O)C=C2N1C

  • Target

    Apoptosis

  • Shipping Conditions

    Room temperature

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Variant Variant total Quantity Price Variant total
5 mgQM-0013418-01
5 mgQM-0013418-01
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10 mgQM-0013418-02
10 mgQM-0013418-02
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25 mgQM-0013418-03
25 mgQM-0013418-03
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MM927 [CAS 3065567-21-4]

MM927 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.