MMAF (GMP) [CAS 745017-94-1]
MMAF (GMP) [CAS 745017-94-1]
SKU:QM-0072047
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Product Details
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Description
MMAF (Monomethylauristatin F) GMP is a GMP grade MMAF. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. MMAF (Monomethylauristatin F) is a potent tubulin polymerization inhibitor and is used as a antitumor agent. MMAF (Monomethylauristatin F) is widely used as a cytotoxic component of antibody-drug conjugates (ADCs) such as vorsetuzumab mafodotin and SGN-CD19A[1][2][3].
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CAS Number
[745017-94-1]
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Molecular Formula
C39H65N5O8
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Molecular Weight
731.96
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Smiles
CC(C)[C@H](NC)C(N[C@H](C(N([C@@H]([C@@H](C)CC)[C@H](OC)CC(N1CCC[C@@]1([H])[C@H](OC)[C@@H](C)C(N[C@H](C(O)=O)CC2=CC=CC=C2)=O)=O)C)=O)C(C)C)=O
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Target
ADC Payload; Microtubule/Tubulin
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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Hazard Statement
H302-H315-H319-H335
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Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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MMAF (GMP) [CAS 745017-94-1]
MMAF (GMP) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.