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MMAF (sodium) (GMP) [CAS 1799706-65-2]
MMAF (sodium) (GMP) [CAS 1799706-65-2]
SKU:QM-0072046
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Product Details
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Description
MMAF sodium GMP is a GMP grade MMAF (sodium). MMAF sodium (Monomethylauristatin F sodium) is a potent tubulin polymerization inhibitor and is used as a antitumor agent. MMAF sodium (Monomethylauristatin F sodium) is widely used as a cytotoxic component of antibody-drug conjugates (ADCs) such as Vorsetuzumab mafodotin and SGN-CD19A[1][2][3].
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CAS Number
[1799706-65-2]
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Molecular Formula
C39H64N5NaO8
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Molecular Weight
753.94
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Smiles
CC[C@H](C)[C@@H]([C@@H](CC(N1[C@@H](CCC1)[C@@H]([C@@H](C)C(N[C@H](C(O[Na])=O)CC2=CC=CC=C2)=O)OC)=O)OC)N(C([C@H](C(C)C)NC([C@H](C(C)C)NC)=O)=O)C
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Target
ADC Payload; Microtubule/Tubulin
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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MMAF (sodium) (GMP) [CAS 1799706-65-2]
MMAF (sodium) (GMP) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.