MMK1 (TFA)

MMK1 TFA is a potent and selective human formyl peptide receptor like-1 (FPRL-1/FPR2) agonist with EC50s of 10000 nM for FPRL-1 and FPR1, respectively. MMK1 TFA is a potent chemotactic and calcium-mobilizing agonist. MMK1 TFA potently activates phagocytic leukocytes and enhances Pertussis Toxin-sensitive production by human monocytes of proinflammatory cytokines IL-1b and IL-6. MMK1 TFA exerts anxiolytic-like activity[1][2][3][4].

C75H123N19O18S.xC2HF3O2

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Calcium Channel; Formyl Peptide Receptor (FPR)

Calcium Channel

10 mM in DMSO

Room temperature