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SKU:QM-0141018-01
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MMRi64 disrupts Mdm2-MdmX interactions. MMRi64 downregulates Mdm2 and MdmX in leukemia cells. MMRi64 induces p53 accumulation, and induces the apoptotic arm of the p53 pathway in leukemia/lymphoma cells. MMRi64 can be used for cancer research[1].
[430458-66-5]
C22H17Cl2N3O
410.3
OC1=C2N=CC=CC2=CC=C1C(C3=CC=CC(Cl)=C3Cl)NC4=NC=CC(C)=C4
Apoptosis; MDM-2/p53
98
DMSO : 100 mg/mL (ultrasonic)
-20°C, 3 years; 4°C, 2 years (Powder)
Room Temperature
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MMRi64 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.