MNN-02-155 [CAS 3067681-22-2]

MNN-02-155 is a bivalent molecular glue with with dual binding to p300/CBP and BCL6. MNN-02-155 induces potent activation of the BCL6-target reporter gene and cell death. MNN-02-155 can be used for the study of diffuse large B cell lymphomas (DLBCLs) [1].

[3067681-22-2]

C56H68ClF2N15O7

1136.69

O=C(N1CC2=C(CC1)N(C3CCN(CC3)C(CCCCNC(C4CCN(CC4)C5=NC=C(C(NC6=CC(C=C(C(N7C)=O)OCC(NC)=O)=C7C(OC)=C6)=N5)Cl)=O)=O)N=C2N8C9=C(CCC8)C=C(C%10=CN(C)N=C%10)C(C(F)F)=C9)NC

BCL6; Histone Acetyltransferase; Molecular Glues

Room temperature