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Mobocertinib [CAS 1847461-43-1]
Mobocertinib [CAS 1847461-43-1]
SKU:QM-0145226-01
£62.26 GBP
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Product Details
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Description
Mobocertinib (TAK-788) is an orally active and irreversible EGFR/HER2 inhibitor. Mobocertinib potently inhibits oncogenic variants containing activating EGFRex20ins mutations with selectivity over wild-type EGFR. Mobocertinib can be used in NSCLC research[1][2].
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CAS Number
[1847461-43-1]
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Molecular Formula
C32H39N7O4
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Molecular Weight
585.7
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Smiles
O=C(C1=CN=C(NC2=CC(NC(C=C)=O)=C(N(CCN(C)C)C)C=C2OC)N=C1C3=CN(C)C4=C3C=CC=C4)OC(C)C
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Target
EGFR
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Isoform
EGFR/ErbB1/HER1; ErbB2/HER2
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Purity
99.09
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Solubility
DMSO : 25 mg/mL (ultrasonic; warming; heat to 80°C)
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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Hazard Statement
H302, H315, H319, H335
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Precautions
H302, H315, H319, H335
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Mobocertinib [CAS 1847461-43-1]
Mobocertinib is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.