Moveltipril (calcium) [CAS 85921-53-5]

Moveltipril calcium (MC-838 calcium) is an orally active angiotensin converting enzyme (ACE) inhibitor with antihypertensive activity. Moveltipril calcium binds via a stable thioester bond and exhibits relative resistance to enzymatic hydrolysis in rat liver homogenate. Moveltipril calcium effectively inhibits ACE extracted from rabbit lung in a concentration-dependent manner. Moveltipril calcium is able to highly specifically inhibit the contractile response to angiotensin-I (AI) in free rat aortic rings and guinea pig ileum preparations, while enhancing the contractile response to calcitonin[1].

[85921-53-5]

C19H29N2O5S.1/2Ca

417.51

O=C(C1CCCCC1)N[C@H](C)C(SC[C@@H](C)C(N2[C@@H](CCC2)C([O-])=O)=O)=O.[0.5].[Ca+2]

Angiotensin-converting Enzyme (ACE)

Room temperature