MOZ-IN-3

MOZ-IN-3 (Compound 6j) is a KAT6A (MOZ) acetyltransferase inhibitor (IC50: 30 nM) . MOZ-IN-3 has antitumor activity against four different myeloid leukemia cell lines (HL-60, U937, SKNO-1, K562) . MOZ-IN-3 has favorable metabolic stability and pharmacokinetics[1].

C17H13FN2O3S

344.36

FC1=C(C(CNS(=O)(C2=CC=CC3=C2N=CC=C3)=O)=O)C=CC=C1

Histone Acetyltransferase

98.75

DMSO : ≥ 200 mg/mL

-20°C, 3 years; 4°C, 2 years (Powder)

Room Temperature