MRS2500 (tetraammonium) [CAS 630103-23-0]

MRS2500 tetraammonium is a potent, selective and stable antagonist of the P2Y1 receptor (Ki=0.78 nM for recombinant human P2Y1 receptor) . MRS2500 tetraammonium inhibits the ADP-induced aggregation of human platelets with an IC50 value of 0.95 nM. Antithrombotic activity[1][2][3].

[630103-23-0]

C13H30IN9O8P2

629.28

O=P(O[C@@H]1[C@]2(COP(O[NH4])(O[NH4])=O)C[C@]2([H])[C@@H](N3C=NC4=C(NC)N=C(I)N=C34)C1)(O[NH4])O[NH4]

P2Y Receptor

P2Y1 Receptor

99.91

H2O : 50 mg/mL (ultrasonic)

-20°C (Powder, sealed storage, away from moisture)

Blue Ice