MRS542 [CAS 163152-31-6]

MRS542 is a nucleoside A3 AR antagonist with a pKi of 8.74. MRS542 also acts as a partial agonist (pEC50 = 7.76) in promoting β-arrestin translocation. MRS542 can be converted into an agonist by LUF6000. MRS542 can be used for cardiovascular disease research[1][2].

[163152-31-6]

C17H17ClIN5O4

517.71

N(CC1=CC(I)=CC=C1)C2=C3C(N(C=N3)[C@@H]4O[C@H](CO)[C@@H](O)[C@H]4O)=NC(Cl)=N2

Adenosine Receptor; Arrestin

Adenosine A3 receptor (A3R)

Room temperature