MS159 [CAS 3031353-59-7]

MS159 is a potent nuclear receptor binding SET structural domain protein 2 (NSD2) PROTACdegrader. MS159 inhibits the growth of tumour cells. MS159 is a useful chemical tool for exploring the role of NSD2 in health and disease[1].

[3031353-59-7]

C43H40N8O10

828.83

O=C(NCCCOC1=CN=C(C=C1)NC(C2=CC=C(C=C2)CN(C3CC3)C(C4=CC=C5NC(COC5=C4)=O)=O)=O)CNC6=CC=CC7=C6C(N(C7=O)C8CCC(NC8=O)=O)=O

PROTACs

99.38

DMSO : 100 mg/mL (ultrasonic; heat to 60°C)

4°C (Powder, sealed storage, away from moisture and light)

Room Temperature