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MS37452 [CAS 423748-02-1]

MS37452 [CAS 423748-02-1]

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QM-0139584-01

£94.75 GBP
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Product Details

  • Description

    MS37452 is a potent inhibitor of CBX7 chromodomain binding to H3K27me3, with a Kd of 27.7 μM. MS37452 can derepress transcription of polycomb repressive complex target gene p16/CDKN2A by displacing CBX7 binding to the INK4A/ARF locus in prostate cancer cells[1].

  • CAS Number

    [423748-02-1]

  • Molecular Formula

    C22H26N2O5

  • Molecular Weight

    398.45

  • Smiles

    CC1=CC(OCC(N2CCN(CC2)C(C3=CC=CC(OC)=C3OC)=O)=O)=CC=C1

  • Target

    Histone Methyltransferase

  • Purity

    99.81

  • Solubility

    DMSO : 100 mg/mL (ultrasonic)

  • Storage Conditions

    -20°C, 3 years; 4°C, 2 years (Powder)

  • Shipping Conditions

    Room Temperature

  • Hazard Statement

    H302, H315, H319, H335

  • Precautions

    H302, H315, H319, H335
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Variant Variant total Quantity Price Variant total
5 mgQM-0139584-01
5 mgQM-0139584-01
£94.75/ea		 £0.00
£94.75/ea £0.00
10 mM - 1 mLQM-0139584-02
10 mM - 1 mLQM-0139584-02
£101.50/ea		 £0.00
£101.50/ea £0.00
10 mgQM-0139584-03
10 mgQM-0139584-03
£140.88/ea		 £0.00
£140.88/ea £0.00
25 mgQM-0139584-04
25 mgQM-0139584-04
£325.81/ea		 £0.00
£325.81/ea £0.00
50 mgQM-0139584-05
50 mgQM-0139584-05
£539.64/ea		 £0.00
£539.64/ea £0.00
100 mgQM-0139584-06
100 mgQM-0139584-06
£890.78/ea		 £0.00
£890.78/ea £0.00
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MS37452 [CAS 423748-02-1]

MS37452 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.