MS83 epimer 1

MS83 epimer 1 is the epimer of MS83. MS83 is a proof-of-concept PROTAC by linking the KEAP1 ligand to a BRD4/3/2 binder[1].

C52H55ClN10O8S2

1047.64

O=S1(C2=CC=CC=C2O[C@H](C)CN1CC3=CC(C(C4=CC(OCCNC(CNC(C[C@H]5C6=NN=C(C)N6C7=C(C(C)=C(C)S7)C(C8=CC=C(Cl)C=C8)=N5)=O)=O)=C(N(C)N=N9)C9=C4)CC(OCC)=O)=CC=C3C)=O

PROTACs

98.36

10 mM in DMSO

-20°C, 3 years; 4°C, 2 years (Powder)

Room Temperature