MS9715

MS9715 is a potent and seletive NSD3-targeting PROTAC. MS9715 is designed by BI-9321, which binds NSD3’s PWWP1 domain, with an E3 ligase VHL ligand. MS9715 has the potental for NSD3-dependent cancer treatment research[1].

C58H74FN9O5S

1028.33

O=C(NCCCCCCCCC(N[C@@H](C(C)(C)C)C(N1[C@H](C(N[C@@H](C)C2=CC=C(C3=C(C)N=CS3)C=C2)=O)C[C@@H](O)C1)=O)=O)CCCNCC4=CC(C)=C(C5=C(C6=CC=NC7=C6C=CC(F)=C7)N(C)C=N5)C(C)=C4

Histone Methyltransferase; PROTACs

99.48

DMSO : 100 mg/mL (ultrasonic)

-20°C, 3 years; 4°C, 2 years (Powder)

Room Temperature