MSG606 (TFA)

MSG606 TFA is a selective melanocortin 1 receptor (MC1R) antagonist. MSG606 TFA can abolish the neuroprotective effects of BMS-470539 (MC1R agonist). MSG606 TFA can inhibit cancer cell proliferation and transition from the G1 to the S phase. MSG606 TFA can delay pain hypersensitivity and reduce cholesterol levels. MSG606 TFA can be used for the researches of cancer, inflammation, neurological and metabolic disease, such as breast cancer and subarachnoid hemorrhage (SAH)[2][3][4].

C62H82N20O13S.xC2HF3O2

OC(C(F)(F)F)=O.O=C([C@@H](NC([C@H](NC([C@@H](NC(CNC(CCCSC[C@H](NC1=O)C(N[C@@H](CC(O)=O)C(N[C@@H](CCCNC(N)=N)C(N[C@H](C(NCC(N)=O)=O)CC2=CC=CC=C2)=O)=O)=O)=O)=O)CC3=CN=CN3)=O)CC4=CC=CC=C4)=O)CCCNC(N)=N)N[C@@H]1CC5=CNC6=CC=CC=C56

Melanocortin Receptor

MC1R

10 mM in DMSO

-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

Room Temperature