MSIRK [CAS 593267-11-9]

MSIRK (G-Protein βγ Binding Peptide) is an cell-permeable activator of ERK1/2, with EC50 of 2.5-5 μM. mSIRK disrupts the interaction between α and βγ subunits and promotes α subunit dissociation without stimulating nucleotide exchange[1].

[593267-11-9]

C93H150N20O25

1948.31

OC(C=C1)=CC=C1C[C@H](NC(CNC([C@H](CC(C)C)NC([C@H]([C@@H](C)CC)NC([C@H](CC(N)=O)NC([C@H](CC(C)C)NC([C@H](C)NC([C@H](CCCCN)NC([C@H](CCCNC(N)=N)NC([C@H]([C@@H](C)CC)NC([C@H](CO)NC(CCCCCCCCCCCCC)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)C(N2[C@@H](CCC2)C(N[C@@H](CC(O)=O)C(N[C@H](C(N[C@H](C(O)=O)CC(O)=O)=O)CC3=CC=C(C=C3)O)=O)=O)=O

ERK

99.33

DMSO : 100 mg/mL (ultrasonic)

-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

Blue Ice