Muramyl dipeptide [CAS 53678-77-6]

Muramyl dipeptide (MDP) is a synthetic immunoreactive peptide, consisting of N-acetyl muramic acid attached to a short amino acid chain of L-Ala-D-isoGln. Muramyl dipeptide is an inducer of bone formation through induction of Runx2. Muramyl dipeptide directly enhances osteoblast differentiation by up-regulating Runx2 gene expression through MAPK pathways. Muramyl dipeptide is a NLRP1 agonist[1][2].

[53678-77-6]

C19H32N4O11

492.48

CC(N[C@@H](C=O)[C@H]([C@H](O)[C@H](O)CO)O[C@H](C)C(N[C@@H](C)C(N[C@@H](C(N)=O)CCC(O)=O)=O)=O)=O

NOD-like Receptor (NLR) ; p38 MAPK

NLRP1; p38 MAPK

10mM

98

DMSO : 100 mg/mL (ultrasonic) |H2O : 50 mg/mL (ultrasonic)

-20°C, 3 years (Powder)

Blue Ice

H315, H319

H315, H319