MY33-3 is a potent and selective inhibitor of receptor protein tyrosine phosphatase (RPTP) β/ζ, with an IC50 of ~0.1 μM. MY33-3 also inhibits PTP-1B (IC50 ~0.7 μM) . MY33-3 can reduce ethanol consumption and alleviate Sevoflurane-induced neuroinflammation and cognitive dysfunction[1][2][3].
CAS Number
[2204280-41-9]
Molecular Formula
C16H13F6NS2
Molecular Weight
397.4
Smiles
FC(SC1=CC=C(CNCC2=CC=C(SC(F)(F)F)C=C2)C=C1)(F)F
Target
Phosphatase
Purity
99.53
Solubility
DMSO : 10 mg/mL (ultrasonic; warming; heat to 60°C)