Myristoyl coenzyme A (lithium) [CAS 187100-75-0]

Myristoyl coenzyme A lithium is lithium-labeled myristoylated coenzyme A (CoA) . Myristoylation is an essential process in viruses and is generally controlled by N-myristoyltransferase (NMT) . And NMT is more active in colon epithelial tumors than in normal cells. Reduced Ccoenzyme A (CoA) is known to be a key regulator of NMT activity, whereas oxidized CoA does not allow NMT to promote myristoylation. Myristoyl coenzyme A blocks the demyristoylation process and has potential anticancer and antiviral mechanisms.

[187100-75-0]

C35H62N7O17P3S.xLi

O=C(SCCNC(CCNC([C@H](O)C(C)(C)COP(OP(OC[C@@H]1[C@@H](OP(O)(O)=O)[C@@H](O)[C@]([H])(N2C=NC3=C(N)N=CN=C32)O1)(O)=O)(O)=O)=O)=O)CCCCCCCCCCCCC.[Li].[x]

Endogenous Metabolite

Human Endogenous Metabolite

97

10 mM in DMSO

-20°C (Powder, sealed storage, away from moisture and light)

Blue Ice