N-3-oxo-dodecanoyl-L-homoserine lactone [CAS 168982-69-2]
N-3-oxo-dodecanoyl-L-homoserine lactone [CAS 168982-69-2]
SKU:QM-0138476-01
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Product Details
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Description
N-3-oxo-dodecanoyl-L-Homoserine lactone (3-oxo-C12-HSL) is a bacterial quorum-sensing signaling molecule produced by P. aeruginosa and strains of the B. cepacia complex[1][2].Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density.N-3-oxo-dodecanoyl-L-Homoserine lactone induces the production of IL-8 in 16HBE human bronchial epithelial cells[3].
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CAS Number
[168982-69-2]
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Molecular Formula
C16H27NO4
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Molecular Weight
297.39
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Smiles
CCCCCCCCCC(CC(N[C@@H]1C(OCC1)=O)=O)=O
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Target
Apoptosis; Bacterial; Caspase; ERK; NF-κB; Reactive Oxygen Species (ROS)
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Concentration
10mM
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Purity
99.88
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Solubility
DMSO : 100 mg/mL (ultrasonic) |H2O : < 0.1 mg/mL (ultrasonic; warming; heat to 60°C)
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Storage Conditions
4°C (Powder, protect from light)
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Shipping Conditions
Room Temperature
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Hazard Statement
H302
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Precautions
H302
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N-3-oxo-dodecanoyl-L-homoserine lactone [CAS 168982-69-2]
N-3-oxo-dodecanoyl-L-homoserine lactone is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.