N-Acetyl-4-S-cysteaminylphenol [CAS 91281-32-2]
N-Acetyl-4-S-cysteaminylphenol [CAS 91281-32-2]
SKU:QM-0114631-01
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Product Details
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Description
N-Acetyl-4-S-mercaptoaminophenol (N-Ac-4-S-CAP) is a compound that is selectively cytotoxic to melanocytes of black mouse hair follicles. It can cause 98% depigmentation of black mouse hair follicles. N-Ac-4-S-CAP can produce visible changes in hair follicle melanocytes 4 hours after intraperitoneal injection, including aggregation of melanin granules and nuclear condensation. Electron microscopy observations showed that it caused progressive destruction of melanocytes, including swelling of membranous organelles, nuclear condensation, and cytoplasmic vacuolation, ultimately leading to complete cell necrosis. N-Ac-4-S-CAP has a specific cytotoxic effect on melanocytes that actively produce eumelanin, but may not affect precursor or dormant melanocytes. These properties suggest that N-Ac-4-S-CAP may have potential application value in the treatment of melanoma or skin whitening.
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CAS Number
[91281-32-2]
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Molecular Formula
C10H13NO2S
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Molecular Weight
211.28
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Smiles
O=C(NCCSC1=CC=C(O)C=C1)C
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Target
DNA/RNA Synthesis; Thymidylate Synthase; Tyrosinase
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Shipping Conditions
Room temperature
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Hazard Statement
H302-H315-H319-H335
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Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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N-Acetyl-4-S-cysteaminylphenol [CAS 91281-32-2]
N-Acetyl-4-S-cysteaminylphenol is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.