N-Acetyldesloratadine [CAS 117796-52-8]
N-Acetyldesloratadine [CAS 117796-52-8]
SKU:QM-0138820-01
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Product Details
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Description
N-Acetyldesloratadine (SCH-37370) is a potent, orally active dual antagonist of platelet-activating factor (PAF) and histamine. N-Acetyldesloratadine inhibits PAF-induced aggregation of human platelets, with an IC50 of 0.6 µM. N-Acetyldesloratadine can be used for the study of allergic diseases, such as asthma[1].
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CAS Number
[117796-52-8]
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Molecular Formula
C21H21ClN2O
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Molecular Weight
352.86
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Smiles
ClC1=CC=C2C(CCC3=CC=CN=C3/C2=C4CCN(CC\4)C(C)=O)=C1
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Target
Histamine Receptor; Platelet-activating Factor Receptor (PAFR)
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Purity
99.93
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Solubility
10 mM in DMSO
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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Hazard Statement
H302, H315, H319, H335
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Precautions
H302, H315, H319, H335
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N-Acetyldesloratadine [CAS 117796-52-8]
N-Acetyldesloratadine is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.