N-Acetylneuraminic acid [CAS 131-48-6]
N-Acetylneuraminic acid [CAS 131-48-6]
SKU:QM-0161579-01
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Product Details
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Description
N-Acetylneuraminic acid (NANA; Lactaminic acid), a nonphenolic structure, is the predominant form of sialic from Collocalia esculenta. N-Acetylneuraminic acid plays a biological role in myocardial injury, melanoma and viral or bacterial infection. N-Acetylneuraminic acid inhibits melanogenesis by reducing tyrosinase activity and triggers myocardial injury in vitro and in vivo by activation of the Rho/Rho-associated signaling pathway through binding to RhoA and Cdc42. N-Acetylneuraminic acid may prevent high fat diet (HFD) -induced inflammation and oxidative stress, thereby prevents hyperlipidemia-associated inflammation and oxidative stress. N-Acetylneuraminic acid is promising for research in the field of melanoma, coronary artery, obesity-related diseases and hyperlipidemia[1][2][3][4][5].
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CAS Number
[131-48-6]
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Molecular Formula
C11H19NO9
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Molecular Weight
309.27
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Smiles
OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](NC(C)=O)[C@@H](O)CC(C(O)=O)=O
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Target
Endogenous Metabolite; Influenza Virus; Ras; Tyrosinase
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Isoform
Human Endogenous Metabolite; Microbial Metabolite
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Concentration
10mM
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Purity
99.95
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Solubility
H2O : ≥ 125 mg/mL
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Storage Conditions
-20°C (Powder, stored under nitrogen)
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Shipping Conditions
Blue Ice
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Hazard Statement
H302, H315, H319, H335
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Precautions
H302, H315, H319, H335
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N-Acetylneuraminic acid [CAS 131-48-6]
N-Acetylneuraminic acid is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.