N-Arachidonoyl-L-serine [CAS 187224-29-9]
N-Arachidonoyl-L-serine [CAS 187224-29-9]
SKU:QM-0004691
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Product Details
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Description
N-Arachidonoyl-L-serine (ARA-S) is an endocannabinoid. N-Arachidonoyl-L-serine induces phosphorylation of Akt and MAPK in endothelial cells. N-Arachidonoyl-L-serine also induces endothelium-dependent vasodilation in isolated rat mesenteric and abdominal aortas. N-Arachidonoyl-L-serine exhibits neuroprotective effects after traumatic brain injury by reducing apoptosis. N-Arachidonoyl-L-serine promotes the opening of KV7.1/KCNE1 channels in mammalian cells and shortens the action potential duration in cardiomyocytes. N-Arachidonoyl-L-serine may be used in research on cardiovascular and cerebrovascular diseases and neurological disorders[1][2][3].
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CAS Number
[187224-29-9]
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Molecular Formula
C23H37NO4
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Molecular Weight
391.54
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Smiles
CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(N[C@H](C(O)=O)CO)=O
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Target
Akt; Apoptosis; p38 MAPK; Potassium Channel
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Shipping Conditions
Room temperature
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Hazard Statement
H225-H350
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Precautions
P210-P233-P240-P241-P242-P243-P280-P303+P361+P353-P370+P378-P403+P235-P405-P501
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N-Arachidonoyl-L-serine [CAS 187224-29-9]
N-Arachidonoyl-L-serine is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.