N-Desmethyl-Apalutamide-15N, d4
N-Desmethyl-Apalutamide-15N, d4
SKU:QM-0096801
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Product Details
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Description
N-Desmethyl-Apalutamide-15N, d4 is the 15N and deuterium labeled isotope of N-Desmethyl-Apalutamide. N-Desmethyl Apalutamide is an active metabolite of Apalutamide. N-Desmethyl Apalutamide is a less potent antagonist of the androgen receptor and is responsible for one-third of the activity of Apalutamide. The formation of N-Desmethyl Apalutamide mediated predominantly by CYP2C8 and CYP3A4. N-Desmethyl Apalutamide is moderate to strong CYP3A4 and CYP2B6 inducer and has an excellent plasma-proteins bound concentration[1][2][3].
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Molecular Formula
C20H9D4F4N4 15NO2S
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Molecular Weight
468.43
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Smiles
O=C([15NH2])C1=CC=C(N(C(N(C2=CC(C(F)(F)F)=C(C#N)N=C2)C3=O)=S)C43C([2H])([2H])CC4([2H])[2H])C=C1F
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Target
Androgen Receptor; Cytochrome P450; Isotope-Labeled Compounds
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Shipping Conditions
Room temperature
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N-Desmethyl-Apalutamide-15N, d4
N-Desmethyl-Apalutamide-15N, d4 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.