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N-Desmethyl-loperamide [CAS 66164-07-6]
N-Desmethyl-loperamide [CAS 66164-07-6]
SKU:QM-0127637-01
£557.87 GBP
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Product Details
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Description
N-Desmethyl-loperamide is a major metabolite of loperamide, a drug that selectively activates peripheral μopioid receptors with a Ki value of 0.16 nM. N-Desmethyl-loperamide is a substrate of the ATP-dependent efflux transporter P-glycoprotein[1][2][3].
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CAS Number
[66164-07-6]
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Molecular Formula
C28H31ClN2O2
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Molecular Weight
463.01
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Smiles
O=C(C(C1=CC=CC=C1)(CCN2CCC(C3=CC=C(C=C3)Cl)(CC2)O)C4=CC=CC=C4)NC
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Target
Opioid Receptor
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Purity
98.36
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Solubility
DMSO : 5.56 mg/mL (ultrasonic; warming; heat to 60°C)
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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Hazard Statement
H302, H315, H319, H335
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Precautions
H302, H315, H319, H335
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N-Desmethyl-loperamide [CAS 66164-07-6]
N-Desmethyl-loperamide is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.