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N-Didesmethyladitoprim [CAS 56066-19-4]
N-Didesmethyladitoprim [CAS 56066-19-4]
SKU:QM-0014479
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Product Details
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Description
N-Didesmethyladitoprim is a metabolite of Aditoprime. Aditoprime is a selective bacterial dihydrofolate reductase (DHFR) inhibitor with IC50s of 47 and 520 nM for E.coli and L.casei DHFR , respectively. Aditoprime inhibits the transformation of dihydrofolic acid to tetrahydrofolic acid. Aditoprime has a broad-spectrum antibacterial activity and excellent pharmacokinetics[1][2][3][4].
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CAS Number
[56066-19-4]
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Molecular Formula
C13H17N5O2
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Molecular Weight
275.31
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Smiles
NC1=NC=C(CC2=CC(OC)=C(C(OC)=C2)N)C(N)=N1
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Target
Antifolate; Bacterial; Drug Metabolite
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Shipping Conditions
Room temperature
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N-Didesmethyladitoprim [CAS 56066-19-4]
N-Didesmethyladitoprim is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.