N-Fmoc-8-aminooctanoic acid [CAS 126631-93-4]
N-Fmoc-8-aminooctanoic acid [CAS 126631-93-4]
SKU:QM-0047884-01
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Product Details
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Description
N-Fmoc-8-aminooctanoic acid can be used as a PROTAC linker in the synthesis of PROTACs. N-Fmoc-8-aminooctanoic acid is an alkane chain with terminal Fmoc-protected amine and carboxylic acid groups. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.
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CAS Number
[126631-93-4]
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Molecular Formula
C23H27NO4
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Molecular Weight
381.46
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Smiles
OC(CCCCCCCNC(OCC1C2=CC=CC=C2C3=C1C=CC=C3)=O)=O
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Target
PROTAC Linkers
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Purity
99.66
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Storage Conditions
Store at room temperature 3 years
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Shipping Conditions
Room Temperature
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Hazard Statement
H302, H315, H319, H335
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Precautions
H302, H315, H319, H335
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N-Fmoc-8-aminooctanoic acid [CAS 126631-93-4]
N-Fmoc-8-aminooctanoic acid is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.