N-Methylcytisine [CAS 486-86-2]

N-Methylcytisine (Caulophylline), a tricyclic quinolizidine alkaloid, exerts hypoglycaemic, analgesic and anti-inflammatory activities. N-methylcytisine is a selective ligand of nicotinic receptors of acetylcholine in the central nervous system and has a high affinity (Kd = 50 nM) to nicotinic acetylcholine receptors (nAChR) from squid optical ganglia[1][2].

[486-86-2]

C12H16N2O

204.27

O=C1C=CC=C2N1C[C@]3([H])CN(C)C[C@@]2([H])C3

NAChR

10mM

99.81

DMSO : 120 mg/mL (ultrasonic) |H2O : 100 mg/mL (ultrasonic)

4°C (Powder, protect from light)

Room Temperature

H302+H312+H332

H302+H312+H332