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N-Undecanoyl-L-homoserine lactone [CAS 216596-71-3]

N-Undecanoyl-L-homoserine lactone [CAS 216596-71-3]

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SKU:QM-0058969

£144.25 GBP
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  • Description

    Quorum sensing is a regulatory system used by bacteria to control gene expression in response to increased cell density. This regulatory process manifests itself in a variety of phenotypes, including biofilm formation and virulence factor production. Coordinated gene expression is achieved through the production, release and detection of small diffusible signaling molecules called autoinducers. N-acylated homoserine lactones (AHLs) comprise a class of such autoinducers, each of which generally consists of a fatty acid coupled to a homoserine lactone (HSL) . Modulation of bacterial quorum-sensing signaling systems to suppress pathogenesis represents a new approach to antimicrobial research for infectious diseases. AHLs differ in acyl length (C4-C18), C3 substitution (hydrogen, hydroxyl, or oxo group), and the presence or absence of one or more carbon-carbon double bonds in the fatty acid chain. These differences confer signaling specificity through the affinity of the LuxR family of transcriptional regulators. C11-HSL has a rare odd-numbered acyl carbon chain and may be a minor quorum-sensing signaling molecule in Pseudomonas aeruginosa strains.

  • CAS Number

    [216596-71-3]

  • Molecular Formula

    C15H27NO3

  • Molecular Weight

    269.38

  • Smiles

    CCCCCCCCCCC(N[C@H]1CCOC1=O)=O

  • Target

    Biochemical Assay Reagents

  • Solubility

    10 mM in DMSO

  • Storage Conditions

    Store at room temperature 3 years

  • Shipping Conditions

    Room Temperature

  • Hazard Statement

    H302, H315, H319, H335

  • Precautions

    H302, H315, H319, H335

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N-Undecanoyl-L-homoserine lactone [CAS 216596-71-3]

N-Undecanoyl-L-homoserine lactone is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.