N2-iso-Butyroyl-7'-O-DMT-morpholinoguanine [CAS 2243974-78-7]

N2-iso-Butyroyl-7'-O-DMT-morpholinoguanine is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7) [1].

[2243974-78-7]

C35H38N6O6

638.71

O=C(N=C(N1)NC(C(C)C)=O)C(N=C2)=C1N2[C@@H](CNC3)O[C@@H]3COC(C4=CC=C(C=C4)OC)(C5=CC=CC=C5)C6=CC=C(C=C6)OC

Nucleoside Antimetabolite/Analog

10 mM in DMSO

Room temperature