N3-PEG3-VC-PAB-MMAF [CAS 2757277-32-8]

N3-PEG3-VC-PAB-MMAF (Comp T-88-5) is a drug-linker conjugate containing the ADC linker N3-PEG3-VC-PAB and the tubulin inhibitor MMAF[1]. N3-PEG3-VC-PAB-MMAF is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

[2757277-32-8]

C66H105N13O17

1352.62

OC([C@H](CC1=CC=CC=C1)NC([C@H](C)[C@H]([C@@]2([H])N(CCC2)C(C[C@@H](OC)[C@H]([C@@H](C)CC)N(C)C([C@H](C(C)C)NC([C@H](C(C)C)N(C)C(OCC3=CC=C(C=C3)NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(COCCOCCOCCN=[N+]=[N-])=O)=O)=O)=O)=O)=O)=O)OC)=O)=O

Drug-Linker Conjugates for ADC

99.95

DMSO : 100 mg/mL

-20°C (Powder, stored under nitrogen)

Blue Ice