N3-TEMPO is a click chemistry reagent containing an azide group. Click chemistry has great potential for use in binding between nucleic acids, lipids, proteins, and other molecules, and has been used in many research fields because of its beneficial characteristics, including high yield, high specificity, and simplicity[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
CAS Number
[63697-61-0]
Molecular Formula
C9H17N4O
Molecular Weight
197.26
Smiles
CC1(C)CC(N=[N+]=[N-])CC(C)(C)N1[O]
Target
ADC Linker
Purity
99.41
Solubility
10 mM in DMSO
Storage Conditions
-20°C (Powder, protect from light, stored under nitrogen)