N4-Acetylcytidine [CAS 3768-18-1]
N4-Acetylcytidine [CAS 3768-18-1]
SKU:QM-0169904-01
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Product Details
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Description
N4-acetylcytidine (N4A) is an endogenous nucleoside metabolite from the degradation of tRNA. N4-Acetylcytidine is formed by N-acetyltransferase 10 and other enzymes. N4-acetylcytidine might sustain NLRP3 inflammasome activation via induction of HMGB1 expression and releasee. N4-Acetylcytidine modifies mRNA, tRNA and rRNA, affecting their stability, translation efficiency (such as enterovirus 71 RNA) . N4-Acetylcytidine is used in the study of cancer, neuroinflammatory diseases, viral infections and obesity[1][2][3][4][5].
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CAS Number
[3768-18-1]
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Molecular Formula
C11H15N3O6
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Molecular Weight
285.25
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Smiles
O=C(N=C(NC(C)=O)C=C1)N1[C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O
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Target
Endogenous Metabolite; Enterovirus; Histone Acetyltransferase; NOD-like Receptor (NLR)
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Isoform
Human Endogenous Metabolite; NLRP3
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Purity
99.66
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Solubility
DMSO : 25 mg/mL (ultrasonic; warming; heat to 60°C)
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Storage Conditions
-20°C, 3 years (Powder)
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Shipping Conditions
Blue Ice
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Hazard Statement
H302, H315, H319, H335
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Precautions
H302, H315, H319, H335
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N4-Acetylcytidine [CAS 3768-18-1]
N4-Acetylcytidine is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.