NA-1-157

NA-1-157 is a potent irreversible covalent inhibitor of the GES-5 carbapenemase, with a MIC of 0.5 μg/mL[1].

C17H25N3O5S

383.46

C[C@]1([C@H]2[C@H](O)C)CC(S[C@@H]3CC(C(N(C)C)=O)NC3)=C(C(O)=O)N1C2=O

Bacterial

10 mM in DMSO

Room temperature