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NADH-IN-3

NADH-IN-3

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SKU:QM-0012768

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  • Description

    NADH-IN-3 (Compound C4-1) is a NADH inhibitor with a MIC of 4 μg/mL (13.042 μM) for type II NADH dehydrogenase of Mycobacterium tuberculosis (Mtb). NADH-IN-3 significantly interrupts ATP synthesis, shows potent inhibitory effects against mono (Rifampicin and Isoniazid (HY-B0329) ) and multi drug-resistant (Mtb) strains and an anti-bactericidal activity against HepG2 cells with low cytotoxicity (SI: 16.52).

  • Molecular Formula

    C15H18N2OS2

  • Molecular Weight

    306.45

  • Smiles

    CC(C1=CC2=C(N=C(S2)SCC(NC3CC3)=O)C=C1)C

  • Target

    Endogenous Metabolite

  • Isoform

    Microbial Metabolite

  • Shipping Conditions

    Room temperature

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NADH-IN-3

NADH-IN-3 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.