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NADPH [CAS 53-57-6]

NADPH [CAS 53-57-6]

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SKU:QM-0138021-01

£94.75 GBP
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  • Description

    NADPH is a coenzyme of glutathione reductase (GR), thioredoxin reductase (TrxR) and NADPH oxidase (NOX), and participates in redox reactions as a hydrogen donor. NADPH has the characteristic of selectively participating in the regulation of cellular redox homeostasis. NADPH exerts antioxidant activity and resists reactive oxygen species (ROS) damage by providing reducing equivalents for the regeneration of glutathione (GSH) and thioredoxin (Trx) ; at the same time, it acts as a substrate of NOX to generate superoxide anions, mediating oxidative stress and immune response. NADPH participates in maintaining the intracellular reducing environment, biosynthesis and regulating gene expression (such as the Nrf2 pathway), and is mainly used in the study of oxidative stress-related diseases (such as cardiovascular diseases, neurodegenerative diseases, cancer) and immune regulation mechanisms[1][2].

  • CAS Number

    [53-57-6]

  • Molecular Formula

    C21H30N7O17P3

  • Molecular Weight

    745.42

  • Smiles

    O=P(O)(O)O[C@H]1[C@H](N2C3=NC=NC(N)=C3N=C2)O[C@@H]([C@H]1O)COP(OP(OC[C@H]4O[C@@H](N5C=C(CC=C5)C(N)=O)[C@@H]([C@@H]4O)O)(O)=O)(O)=O

  • Target

    Endogenous Metabolite

  • Isoform

    Human Endogenous Metabolite

  • Purity

    99.75

  • Solubility

    H2O : 116.67 mg/mL (ultrasonic)

  • Storage Conditions

    4°C (Powder, protect from light)

  • Shipping Conditions

    Room Temperature

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NADPH [CAS 53-57-6]

NADPH is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.