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NADPH oxidase-IN-1 [CAS 2762405-17-2]

NADPH oxidase-IN-1 [CAS 2762405-17-2]

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QM-0150723-01

£238.32 GBP
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Product Details

  • Description

    NADPH oxidase-IN-1 is an orally active NADPH oxidase (Nox) inhibitor, related with neuronal inflammation. NADPH oxidase-IN-1 can cross the blood-brain barrier (BBB), inhibits Nox2 and Nox4 with IC50s of 1.9 μM and 2.47 μM, respectively. NADPH oxidase-IN-1 suppresses pro-inflammatory cytokines production and LPS-mediated microglial migration, also has in vivo efficacy[1].

  • CAS Number

    [2762405-17-2]

  • Molecular Formula

    C20H27N3O2S

  • Molecular Weight

    373.51

  • Smiles

    CN(C1=CC=C(C=C1)/C=C2C(N(C(N\2C)=S)C3CCCCC3)=O)CCO

  • Target

    NADPH Oxidase

  • Isoform

    NOX2; NOX4

  • Purity

    99.69

  • Solubility

    DMSO : 62.5 mg/mL (ultrasonic; warming; heat to 60°C)

  • Storage Conditions

    -20°C, 3 years; 4°C, 2 years (Powder)

  • Shipping Conditions

    Room Temperature
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Variant Variant total Quantity Price Variant total
5 mgQM-0150723-01
5 mgQM-0150723-01
£238.32/ea		 £0.00
£238.32/ea £0.00
10 mM - 1 mLQM-0150723-02
10 mM - 1 mLQM-0150723-02
£256.55/ea		 £0.00
£256.55/ea £0.00
10 mgQM-0150723-03
10 mgQM-0150723-03
£351.32/ea		 £0.00
£351.32/ea £0.00
25 mgQM-0150723-04
25 mgQM-0150723-04
£652.64/ea		 £0.00
£652.64/ea £0.00
50 mgQM-0150723-05
50 mgQM-0150723-05
£1,003.77/ea		 £0.00
£1,003.77/ea £0.00
100 mgQM-0150723-06
100 mgQM-0150723-06
£1,556.60/ea		 £0.00
£1,556.60/ea £0.00
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NADPH oxidase-IN-1 [CAS 2762405-17-2]

NADPH oxidase-IN-1 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.