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Nampt-IN-10 [CAS 2241015-68-7]
Nampt-IN-10 [CAS 2241015-68-7]
SKU:QM-0050573
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Product Details
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Description
Nampt-IN-10 (Compound 4) is an efficient inhibitor of nicotinamide phosphoribosyltransferase (NAMPT) . Nampt-IN-10 exhibits nanomolar-level inhibitory activity against cell lines such as MDA-MB453, NCI-N87, and NCI-H526. Nampt-IN-10 can be used as an ADC payload, and the ADC constructed with it as the core demonstrates significant anti-tumor activity[1].
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CAS Number
[2241015-68-7]
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Molecular Formula
C27H28FN5O2
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Molecular Weight
473.54
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Smiles
FC(C=C1NC([C@@H]2[C@@H](C3=CN=CC=C3)C2)=O)=C(C=C1)CNC(C4=CC=C(N5CCNCC5)C=C4)=O
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Target
ADC Payload; NAMPT
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Shipping Conditions
Room temperature
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Nampt-IN-10 [CAS 2241015-68-7]
Nampt-IN-10 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.