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Nampt-IN-10 (trihydrochloride)
Nampt-IN-10 (trihydrochloride)
SKU:QM-0067215
Price on request
Quantity
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Product Details
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Description
Nampt-IN-10 trihydrochloride (compound 4) is a Nicotinamide Phosphoribosyltransferase (NAMPT) inhibitor. Nampt-IN-10 trihydrochloride shows cellular potency to A2780 and CORL23 cell lines with IC50 values of 5 and 19 nM, respectively. Nampt-IN-10 trihydrochloride can be used as a novel non-antimitotic payload for antibody-drug conjugate (ADC) [1].
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Molecular Formula
C27H31Cl3FN5O2
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Molecular Weight
582.92
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Smiles
FC(C=C1NC([C@@H]2[C@@H](C3=CN=CC=C3)C2)=O)=C(C=C1)CNC(C4=CC=C(N5CCNCC5)C=C4)=O.[H]Cl.[H]Cl.[H]Cl
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Target
NAMPT
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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Nampt-IN-10 (trihydrochloride)
Nampt-IN-10 (trihydrochloride) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.