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Naporafenib [CAS 1800398-38-2]
Naporafenib [CAS 1800398-38-2]
SKU:QM-0137333-01
£238.32 GBP
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Product Details
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Description
Naporafenib (LXH254) is a potent, selective, orally active, type II BRAF and CRAF inhibitor, with IC50 values of 0.072 and 0.21 nM against CRAF and BRAF, respectively[1][2].
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CAS Number
[1800398-38-2]
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Molecular Formula
C25H25F3N4O4
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Molecular Weight
502.49
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Smiles
CC1=CC=C(NC(C2=CC(C(F)(F)F)=NC=C2)=O)C=C1C3=CC(N4CCOCC4)=NC(OCCO)=C3
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Target
Bcr-Abl; p38 MAPK; Raf
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Isoform
Abl; B-Raf; C-Raf; p38α
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Purity
99.9
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Solubility
DMSO : 100 mg/mL (ultrasonic)
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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Hazard Statement
H302
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Precautions
H302
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Naporafenib [CAS 1800398-38-2]
Naporafenib is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.