NCI126224 [CAS 65974-52-9]

NCI126224 is a TLR4 signaling inhibitor. NCI126224 suppress LPS -induced production of NF-κB, TNF-α, IL-1β, and NO in the nanomolar-low micromolar range. NCI126224 can be used for the research of inflammatory diseases[1].

[65974-52-9]

C12H11NO6

265.22

O=C(/C(C(OC)=O)=C\C1=C([N+]([O-])=O)C=CC=C1)OC

Toll-like Receptor (TLR)

10mM

99.88

DMSO : 125 mg/mL (ultrasonic)

-20°C, 3 years; 4°C, 2 years (Powder)

Room Temperature