NDT-19795 [CAS 2272917-12-9]

NDT-19795 is an effective inhibitor of the NLRP3 inflammasome with an IC50 value of 66 nM in the PBMC method and 4.7 μM in the WB method. NDT-19795 is a carboxylic acid-active substance that can be converted from NT-0796 within cells. NDT-19795 can be used for the study of neurological diseases[1].

[2272917-12-9]

C20H21N3O4

367.4

OC([C@@H](CC1=NC=CC=N1)OC(NC2=C3C(CCC3)=CC4=C2CCC4)=O)=O

NOD-like Receptor (NLR)

99.16

DMSO : 100 mg/mL (ultrasonic)

-20°C, 3 years; 4°C, 2 years (Powder)

Room Temperature