Name: NecroX-7 [CAS 1120332-55-9]
Brand: QuantiMol
SKU: QM-0076991-01
Price: 238.32 GBP
Availability: InStock

Product Details

Description
NecroX-7 is a potent free radical scavenger and a HMGB1 (high-mobility group box 1) inhibitor. NecroX-7 can be used as an antidote to acetaminophen toxicity. NecroX-7 exerts a protective effect by preventing the release of HMGB1 in ischemia/reperfusion injury. NecroX-7 inhibits the HMGB1-induced release of TNF and IL-6, as well as the expression of TLR-4 and receptor for advanced glycation end products. NecroX-7 can be used graft-versus-host disease (GVHD) research[1].
CAS Number
[1120332-55-9]
Molecular Formula
C24H29N3O3S
Molecular Weight
439.57
Smiles
O=S1(CCN(CC1)CC2=CC3=C(C(NC4CCOCC4)=C2)NC(C5=CC=CC=C5)=C3)=O
Target
Interleukin Related; Reactive Oxygen Species (ROS) ; TNF Receptor; Toll-like Receptor (TLR)
Isoform
IL-6; TLR4
Purity
99.69
Solubility
DMSO : 100 mg/mL (ultrasonic)
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Shipping Conditions
Room Temperature

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Variant	Variant total	Quantity	Price	Variant total
5 mgQM-0076991-01	5 mgQM-0076991-01 £238.32/ea	£0.00	Quantity	£238.32/ea	£0.00

10 mM - 1 mLQM-0076991-02	10 mM - 1 mLQM-0076991-02 £256.55/ea	£0.00	Quantity	£256.55/ea	£0.00

10 mgQM-0076991-03	10 mgQM-0076991-03 £363.47/ea	£0.00	Quantity	£363.47/ea	£0.00

25 mgQM-0076991-04	25 mgQM-0076991-04 £740.12/ea	£0.00	Quantity	£740.12/ea	£0.00

50 mgQM-0076991-05	50 mgQM-0076991-05 £1,241.91/ea	£0.00	Quantity	£1,241.91/ea	£0.00

100 mgQM-0076991-06	100 mgQM-0076991-06 £2,121.57/ea	£0.00	Quantity	£2,121.57/ea	£0.00

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NecroX-7 [CAS 1120332-55-9]

NecroX-7 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.