Neomycin (sulfate) [CAS 1405-10-3]
Neomycin (sulfate) [CAS 1405-10-3]
SKU:QM-0158407-01
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Product Details
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Description
Neomycin sulfate, an aminoglycoside antibiotic, exerts antibacterial activity through irreversible binding of the nuclear 30S ribosomal subunit, thereby blocking bacterial protein synthesis. Neomycin sulfate is a known phospholipase C (PLC) inhibitor. Neomycin sulfate potently inhibits both nuclear translocation of angiogenin and angiogenin-induced cell proliferation and angiogenesis[1][2].
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CAS Number
[1405-10-3]
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Molecular Formula
C23H52N6O25S3
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Molecular Weight
908.88
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Smiles
O[C@H]1[C@H](O)[C@@H](N)[C@@H](O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O)[C@H]2O[C@@H]3O[C@H](CO)[C@@H](O[C@H]4O[C@@H](CN)[C@@H](O)[C@H](O)[C@H]4N)[C@H]3O)O[C@@H]1CN.[3H2SO4]
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Target
Antibiotic; Bacterial; Phospholipase
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Isoform
Aminoglycoside
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Purity
99.86
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Solubility
DMSO : < 1 mg/mL (ultrasonic; warming; heat to 60°C) |H2O : 250 mg/mL (ultrasonic)
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Storage Conditions
4°C (Powder, sealed storage, away from moisture)
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Shipping Conditions
Room Temperature
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Hazard Statement
H317, H334
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Precautions
H317, H334
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Neomycin (sulfate) [CAS 1405-10-3]
Neomycin (sulfate) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.