Neostenine [CAS 477953-07-4]

Neostenine is a stenine-type Stemona alkaloid, with antitussive activity. Neostenine is also a substrate of P-glycoprotein with high absorptive permeability in Caco-2 monolayer model. Neostenine also shows oral activity for intestinal application[1][2].

[477953-07-4]

C17H27NO2

277.4

CC[C@@H]1[C@]2([H])[C@]3([H])[C@](CCN3CCCC2)([H])[C@@]4([H])[C@]1([H])OC([C@H]4C)=O

P-glycoprotein

10 mM in DMSO

Room temperature