Neu5Ac-2Galβ1-3Glc-oxazoline- (2) Me [CAS 2823367-76-4]

Neu5Ac-2Galβ1-3Glc-oxazoline- (2) Me (Compound G12) is a disaccharide linker. Neu5Ac-2Galβ1-3Glc-oxazoline- (2) Me can be efficiently recognized by the endo-glycosidase Endo-S2 and can be directedly transferred to the conserved N-glycosylation site (Asn297 position) of the antibody's Fc domain through enzymatic catalytic reactions, thereby achieving site-specific modification of the antibody. Neu5Ac-2Galβ1-3Glc-oxazoline- (2) Me can be used for for the synthesis of antibody-conjugated drugs (ADCs) [1].

[2823367-76-4]

C25H40N2O18

656.59

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ADC Linker

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