NF-56-EJ40 [CAS 2380230-73-7]

NF-56-EJ40 is a potent, high-affinity, and highly selective human SUCNR1 (GPR91) antagonist with an IC50 of 25 nM and a Ki of 33 nM, and shows almost no activity towards rat SUCNR1. NF-56-EJ40 has high affinity for humanized rat SUCNR1 with a Ki value of 17.4 nM[1].

[2380230-73-7]

C27H29N3O3

443.54

O=C(NC1=C(CC(O)=O)C=CC=C1)C2=CC=CC(C3=CC=C(CN4CCN(C)CC4)C=C3)=C2

Succinate Receptor 1

99.92

DMSO : 5 mg/mL (ultrasonic) |H2O : 4.55 mg/mL (ultrasonic; adjust pH to 9 with NaOH)

-20°C, 3 years; 4°C, 2 years (Powder)

Room Temperature

H302, H312, H332

H302, H312, H332