NF-κB-IN-10 [CAS 3052257-09-4]

NF-κB-IN-10 (compound E1) is an NF-κB inhibitor that can improve heart failure by reducing oxidative stress and inflammation by regulating Nrf2/NF-κB signaling pathway. NF-κB-IN-10 inhibits LPS-induced NO production and expression of iNOS and COX-2 in RAW264.7 cells. NF-κB-IN-10 can be used in the research of cardiovascular diseases[1].

[3052257-09-4]

C26H32N2O4

436.54

CC(N1N=C(C)CC1C2=C(OC)C=C(OC)C=C2/C=C/C3=CC=C(OCCCC)C=C3)=O

NF-κB

10 mM in DMSO

Room temperature